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氢气潜水医学文献汇总

氢气人体安全性是氢气医学最重要的特点。氢气安全性最重要的证据来自潜水医学,具体就是关于氢气人体和动物潜水研究。
 

潜水技术中氢气使用的压力非常高,或者说剂量极大,研究中除了发现存在一些生理功能影响外,这些影响部分是因为高压产生的效应,没有发现氢气有任何毒性效应,这是氢气可应用于潜水的前提条件。
 

任何用于潜水的气体都必须没有毒性。潜水中使用氢气需要非常时间连续暴露,例如需要几周时间,高压意味着需要非常高的剂量,这样的暴露条件要求任何气体必须对人体没有丝毫毒性。能用于潜水的气体包括空气、氦气、氮气、氢气,大深度情况则只能用氦气和氢气,因为高压空气和氮气会有毒性。所以说氢气和氦气的人体安全性比空气和氮气都高。
 

整理一下氢气潜水的有关文献,对从事氢气医学研究的学者和产业都非常重要,昨天恰好有同行来请教这方面的信息,我花费了一个上午整理了这个目录,希望对大家有帮助。
 

部分重要的文献,我阅读后选择给大家重点介绍。如有全文需要,可留言。
 

新冠疫情面前,一定要服从大局,少出门,静候佳音!
 

l Ball, Robert. (2001). Biochemical decompressionof hydrogen by naturally occurring bacterial flora in pigs: What are theimplications for human hydrogen diving?. Undersea & hyperbaric medicine :journal of the Undersea and Hyperbaric Medical Society, Inc. 28. 55-6.用细菌分解氢气进行潜水减压。

l Fahlman A. On the Physiology of Hydrogen Divingand Its Implication for Hydrogen Biochemical Decompression[D]. Carleton University,Ottawa, ON, Canada., 2000.氢气潜水生理学和生物减压技术

l Rostain J C, Gardette-Chauffour M C, GardetteB. Hydrogen, a gas for diving: a mini review[J]. Undersea and Hyperbaric Med, 1999,26: 62. 氢气潜水小综述

l Kayar S R, Parker E C. Oxygen pulse in guineapigs in hyperbaric helium and hydrogen[J]. Journal of Applied Physiology, 1997,82(3): 988-997.氢气潜水动物实验

l Lillo R S, Parker E C, Porter W R.Decompression comparison of helium and hydrogen in rats[J]. Journal of AppliedPhysiology, 1997, 82(3): 892-901.大鼠氢气和氦气潜水减压的比较

l Abraini J H, Martinez E, Lemaire C, et al.ANXIETY, SENSORIMOTOR AND COGNITIVE PERFORMANCE DURING A HYDROGEN–OXYGEN DIVEAND LONG-TERM CONFINEMENT IN A PRESSURE CHAMBER[J]. Journal of environmentalpsychology, 1997, 17(2): 157-164.(氢氧长期高压暴露对人体的副作用)

l Gardette B, Gortan C, Delauze H G. Heliumin-hydrogen out. A new diving technique[C]//Proceedings of the 23rd AnnualScientific Meeting of the European Underwater and Baromedical Society, Bled(Slovenia). 1997. 这是介绍氢气在潜水中的实用技术,就是如何在实用中使用氢气代替氦气,推荐重点阅读。

l Abraini J H, Gardette-Chauffour M C, MartinezE, et al. Psychophysiological reactions in humans during an open sea dive to500 m with a hydrogen-helium-oxygen mixture[J]. Journal of Applied Physiology,1994, 76(3): 1113-1118.氢氦氧潜水500米(50个大气压)潜水的心理反应。

l Gardette B, Massimelli J Y, Comet M, et al.DEEP HYDROGEN DIVING: HYDRA 10-A 701 MSW RECORD DIVE[J]. 1993.人类最大潜水深度记录700米,是使用的氢气潜水

l Segadal K, Gulsvik A, Nicolaysen G. Respiratorychanges with deep diving[J]. European Respiratory Journal, 1990, 3(1): 101-108.深潜呼吸效应,包含氢气潜水

l Imbert G, Ciesielski T, Fructus X. Safe deepsea diving using hydrogen[J]. Marine Technology Society journal, 1989, 23(4):26-33.使用氢气的安全潜水深度

l Puckett J H, Bartholomew A P. DIVING AT 520M ONHYDROGEN-HELIUM-OXYGEN MIXED GAS FROM DYNAMICALLY POSITIONED DIVING SUPPORTVESSEL ORELIA[J]. 1989.520米氢氦氧潜水

l Gardette B. Compression procedures for mice andhuman hydrogen deep diving COMEX HYDRA program[J]. High pressure nervoussyndrome, 1989, 20: 217-231.人类和小鼠氢潜水项目介绍,高压神经综合征角度

l Ciesielski T, Imbert J P. Hydrogen offshorediving to a depth of 530 m: hydra VIII[C]//Offshore Technology Conference.Offshore Technology Conference, 1989.530米氢气海上潜水试验

l Rostain, Jean-Claude & Gardette-Chauffour,M & Lemaire, C & Naquet, R. (1988). Effects of a H2-He-O2 mixture onthe HPNS up to 450 msw. Undersea biomedical research. 15. 257-70.450米深度氢气潜水

l Imbert, J. & Gortan, C. & Fructus, X.& Ciesielski, T. & Gardette, B.. (1987). Hydra 8: Pre-commercialHydrogen Diving Project. 14. 10.1007/978-94-009-1299-1_13.商业氢气潜水项目介绍

l Gortan C, Delauze H G. Hydra V HydrogenExperimental Dive To 450 Meters[C]//Offshore technology conference. OffshoreTechnology Conference, 1986.氢气试验潜水会议论文

l Edel P. Evaluation of the Use ofHydrogen-Oxygen as a Breathing Gas in Deep-Sea Diving[R]. SEA-SPACE RESEARCH COINC MARRERO LA, 1986.氢气作为潜水气体

l Hills B A. Hydrogen-oxygen mixer apparatus andprocess: U.S. Patent 4,269,791[P]. 1981-5-26.美国氢氧混合技术专利

l Gardette B, Comet M, Gortan C, et al. Life in aHyperbaric Environment: A New O 2-H 2 Breathing Mixture for IndustrialDiving[J]. 1988.

l Brauer R W. Hydrogen as a Diving Gas[J]. 1985.

l Fife W. The use of non-explosive mixtures ofhydrogen and oxygen for diving[J]. 1979.

l Dougherty J J H. Use of H2 as an inert gasduring diving: pulmonary function during H2-O2 breathing at 7.06 ATA[J].Aviation, space, and environmental medicine, 1976,47(6): 618-626.7个大气压氢气潜水对呼吸功能的影响

l Dougherty J H. The Use of Hydrogen as an InertGas During Diving: Pulmonary Functions During Hydrogen-oxygen Breathing atPressures Equivalent to 200 Feet of Sea Water[M]. Naval Submarine MedicalResearch Laboratory, Bureau of Medicine and Surgery, Navy Department, 1974.氢气潜水呼吸系统研究

l Edmonds C, Lowry C, Pennefather J. History ofdiving[J]. 1975.潜水历史其中有关于氢气潜水的早期历史介绍

l Edel P O, Holland J M, Fischer C L, et al.Preliminary studies of hydrogen-oxygen breathing mixtures for deep seadiving[J]. Proc Oceanology International. London: Society for UnderwaterTechnology, 1972: 485-489.氢氧潜水的早期研究

l Nuckols M L, Van Zandt K, Finlayson W S, et al.Hot water heater for diver using hydrogen catalytic reactions: U.S. Patent6,463,925[P]. 2002-10-15.(用氢气给潜水员加热)

l Albert D. Combined diving device andelectrolysis operated oxygen generator: U.S. Patent 3,504,669[P]. 1970-4-7.电解水供氧潜水装置

l Welhan J A, Craig H. Methane, hydrogen andhelium in hydrothermal fluids at 21 N on the East Pacific Rise[M]//Hydrothermalprocesses at seafloor spreading centers. Springer, Boston, MA, 1983:391-409. 东太平洋海底氢气

l Holmstedt G S. The upper limit of flammabilityof hydrogen in air, oxygen, and oxygen-inert mixtures at elevated pressures[J].Combustion and Flame, 1971, 17(3): 295-301.氢气可燃性规律的早期研究
 

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